I just found out that Microsoft office 2010 Beta takes over the Q drive. It doesn't matter that it's already mapped to a network drive. Once the software is installed, the local assignment takes over that drive letter and suddenly all applications that depended on the Q drive network map will no longer function. This is similar to Microsoft taking over the M drive for Microsoft Mail. That didn't go over too well either.
I personally like to assign the Q drive to my quickbooks applications. When one laptop installed Office 2010, I had troubles getting the only machine in the office setup to access the Q drive differently. I took a stab in the dark and did a google search for Q drive issues and found the problem. Hopefully this will help others. I found one procedure that made the Q drive disappear, but it still didn't show up in the network mappable drives.
The Q drive is suppose to be used for online updates. I believe they call it, click and go and acts as a virtual hard drive to Microsoft servers to update Office components.